Treating anxiety and depression with NAC

N-A-C, N-acetylcysteine, has a profound effect on depression and anxiety. It boosts levels of glutathione in the body. In other words it is a very powerful liver detoxifier. Mental illnesses such as depression and anxiety have been linked to have been caused by free radical damage instead of low serotonin or “chemical imbalances”.

The effects are real

Numerous studies have shown that NAC is a useful agent in the treatment of psychiatric disorders as discussed here: It has been clinically proven to help treat symptoms of depression and anxiety. A double blind randomized placebo-controlled trial can be found here:

Why does NAC work?

Acetylcysteine is a glutathione precursor. In other words acetylcysteine is converted into glutathione. Glutathione is an antioxidant that is used by your liver to in effect detox your body.

So what? That is your liver

Research suggests that in some cases mental illness can be caused by toxins that your liver is unable to cleanse from your body in response to a glutathione deficiency. The cutting-edge of mental research is now focusing on the role toxins and oxidative stress play in mental illness.

NAC treat anxiety and depression
Liver and NAC
Why not just take glutathione?

Since NAC is a precursor to glutathione why not just take glutathione instead? While that seems like the logical thing to do it doesn’t work in practice. Evidence shows that NAC is more bioavailable and thus works better.

If its so great how come I’ve never heard of it?

If you do a quick search you will see how cheap NAC is. People who make money off of treating those with anxiety and depression have much more expensive treatments and aren’t likely to promote NAC.

Where can I buy it?

A quick search of “NAC” on Amazon comes up with plenty of results. I personally have had the best luck taking these which contain not only NAC but also phenibut which I wrote about here: